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Experimental design. (A) DMH experiment (n = 10 per group). (B) AOM/DSS experiment (n = 7 per group). Two independent experiments were performed. Cancer induction with DMH was achieved after eight weeks of treatment to generate colon tumorigenesis while AOM induction took two weekly doses to generate aberrant cryptic foci. TBLF was administered for six weeks each third day and sacrificed a week later (black arrow).
