Table 2.
Compound | IC50 (μM) a | |
---|---|---|
Superoxide Anion Generation | Elastase Release | |
5 | 3.8 ± 1.4 *** | >10 |
LY294002 b | 0.4 ± 0.02 *** | 1.5 ± 0.3 *** |
a Concentration necessary for 50% inhibition (IC50). Results are presented as means ± SD (n = 3–4). *** p < 0.001 compared with the control (DMSO). b A phosphatidylinositol-3-kinase inhibitor was used as a positive control.