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. 2017 Sep 1;22(9):1454. doi: 10.3390/molecules22091454

Table 2.

Inhibitory effects of isolated compounds on superoxide anion generation and elastase release by human neutrophils in response to N-formyl-l-methionyl-phenylalanine/cytochalasin B (fMLP/CB).

Compound IC50 (μM) a
Superoxide Anion Generation Elastase Release
5 3.8 ± 1.4 *** >10
LY294002 b 0.4 ± 0.02 *** 1.5 ± 0.3 ***

a Concentration necessary for 50% inhibition (IC50). Results are presented as means ± SD (n = 3–4). *** p < 0.001 compared with the control (DMSO). b A phosphatidylinositol-3-kinase inhibitor was used as a positive control.