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Inhibition activity of tested compounds (1–9) against cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2).
| Compound | IC50COX-1 (µM) | IC50COX-2 (µM) |
|---|---|---|
| 1 | 62.10 ± 3.48 | 51.86 ± 3.28 |
| 4 | 352.32 ± 10.91 | 302.95 ± 8.54 |
| 5 | 384.87 ±14.10 | 321.75 ±13.01 |
| 2 | 124.50 ± 7.61 | 103.8 ± 6.11 |
| 6 | 397.93 ± 7.51 | 370.81 ± 15.06 |
| 7 | 458.67 ± 4.02 | 451.18 ± 12.07 |
| 3 | 133.23 ± 6.91 | 109.02 ± 6.82 |
| 8 | 419.80 ± 8.34 | 405.01 ± 10.26 |
| 9 | 493.97 ± 6.34 | 482.16 ± 10.39 |
