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. 2017 Jun 12;22(6):977. doi: 10.3390/molecules22060977

Scheme 12.

Scheme 12

Use of FARs ((A) Reaction of TFEDMA with methoxy acrylate; (B) with dimethylamino acrylate; (C) with a methylhydrazone) and acrylates to prepare ethyl 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate (DFMMP) with full regioselectivity.