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Identification of compounds and their cytotoxicities in RAW264.7 macrophages: (a) High-performance liquid chromatography (HPLC) chromatogram of Fr. A3-3; (b) chemical structures of compounds 1 and 2; and (c) effects of 1 and 2 on cell viability. Cells were treated with compounds 1 or 2 for 1 h and administered with LPS (1 μg/mL) for 24 h, then cell viability was measured by MTT assay.
