Table 1.
IC50 values of crude MeOH extract of LB (LBM) and partitioned extracts of LBM against NO production.
| Extracts/Fractions | IC50 (μg/mL) | Fractions | IC50 (μg/mL) a |
|---|---|---|---|
| LBM | 71.52 ± 4.52 * | Fr. A5 | 34.27 ± 1.34 |
| Fr. A | 32.70 ± 1.56 Δ | Fr. A3-1 | >50 |
| Fr. B | 64.35 ± 1.23 * | Fr. A3-2 | 18.30 ± 3.55 |
| Fr. C | 40.70 ± 0.92 Δ | Fr. A3-3 | 9.32 ± 1.24 |
| Fr. D | 163.11 ± 2.31 *,Δ | Fr. A3-4 | 26.91 ± 1.46 |
| Fr. A1 | >50 * | Fr. A3-5 | >50 |
| Fr. A2 | 37.58 ± 1.25 | Fr. A3-6 | 27.20 ± 2.72 |
| Fr. A3 | 11.49 ± 0.69 * | Fr. A3-7 | >50 |
| Fr. A4 | >50 * | l-NMMA b | 12.42 ± 2.50 |
Δ p < 0.001 compared with LBM; * p < 0.001 compared with fraction (Fr.) A; a Mean ± SEM for n = 3; b Positive control. IC50: half maximal inhibitory concentration; LBM: crude MeOH extract of LB; NO: nitrite oxide; l-NMMA: NG-Monomethyl-l-arginine Monoacetate.