Table 3.

Association Between Hypothyroidism with Hospitalization Risk, Stratified by Demographics

			Unadjusted		Adjusted		Adjusted (including Amiodarone)
	# of Events	Risk Time	HR [CI]	p	HR [CI]	p	HR [CI]	p
Age, years
<60	19,384	5.76	0.94 [0.93–0.96]	<0.001	0.89 [0.85–0.94]	<0.001	0.92 [0.89–0.94]	<0.001
≥60	33,472	5.43	1.14 [1.12–1.17]		1.05 [0.99–1.11]		1.12 [1.10–1.14]
Sex
Male	19,089	5.48	1.14 [1.12–1.16]	0.06	0.99 [0.93–1.06]	0.28	1.16 [1.13–1.19]	0.11
Female	33,767	5.73	0.94 [0.92–0.96]		0.94 [0.90–0.99]		0.84 [0.82–0.86]
Race
Black	4778	5.71	0.96 [0.93–1.01]	0.07	0.89 [0.75–1.07]	0.57	0.99 [0.98–1.0]	0.66
Non-black	48,078	5.64	1.03 [0.98–1.07]		0.96 [0.92–1.00]		1.01 [0.97–1.1]
Ethnicity
Hispanic	4557	5.74	0.98 [0.95–1.01]	0.26	0.96 [0.85–1.09]	0.83	0.98 [0.94–1.02]	0.36
Non-Hispanic	48,299	5.63	1.14 [1.12–1.16]		0.96 [0.92–1.00]		1.06 [0.98–1.14]

Analyses adjusted for age, sex, race, ethnicity, body mass index, diabetes, hypertension, hyperlipidemia, congestive heart failure, coronary artery disease, and cerebrovascular disease.