Table 1.

Characterization of niosomal formulations

Name	Size (nm)	PDI *	Zeta Potential (mV)	EE% * (NPs)	EE% * (Drug)
Niosomes	118.9 ± 2.1	0.37 ± 0.02	−19.5 ± 0.6	–	–
PEGylated-Niosomes	121.5 ± 1.2	0.21 ± 0.02	−14.3 ± 1.1	–	–
Niosomes/D *	127.1 ± 2.1	0.32 ± 0.01	−18.8 ± 1.2	–	73 ± 1.1
Niosomes/D + M *	129.5 ± 3.6	0.31 ± 0.06	−19.3 ± 0.7	94 ± 2.3	84 ± 1.5
PEGylated-niosomes/D	138.2 ± 0.3	0.23 ± 0.04	−16.6 ± 0.7	–	87 ± 1.6
PEGylated-niosomes/D + M	145.2 ± 1.3	0.24 ± 0.02	−15.2 ± 0.3	90 ± 2.1	83 ± 1.2

* PDI = polydispersity index; D = drug (Carboplatin); M = magnetic NPs (Fe₃O₄@SiO₂); and EE% = entrapment efficiency