Fig. 6. SNAI1 expression stimulates angiogenesis in xenograft tumor models and is associated with angiogenesis markers in human tumor samples.

a, b Macroscopic and microscopic decrease of vascular irrigation in tumors derived from colon cells and Snail1 ko MEFs. c PCAM-1 and Masson staining measurement in xenograft tumors. d Illustration of Masson staining in Snail1 wt or ko MEFs + tumor colon cell-derived xenograft tumors. e Representative images of a patient with SNAI1 expression and high degree of vasculature. f Direct association between SNAI1 expression and the degree of vasculature in human colon tumor samples