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Comparison of k-mer information retained by ORNA, Diginorm and TIS. (a) Represents percentage of unique k-mers retained compared to the original brain dataset (x-axis) for various levels of reduction (y-axis) by the three algorithms. (b) and (c) Represent Spearman’s rank correlation values for TPM values obtained by quantifying expression of Ensembl genes using the unreduced and reduced brain dataset and hESC dataset, respectively
