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. 2018 Aug 1;6(3):31. doi: 10.3390/proteomes6030031

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Signatures of postsynaptic proteome composition in mouse brain regions. (A) Seven integral brain regions in mouse: frontal cortex (CxF), medial cortex (CxM), caudal cortex (CxCA), hippocampus (Hip), striatum (ST), hypothalamus (Hyp), and cerebellum (CB). Color coded according to vertebrate embryological regions (as in (B)). (B) Hierarchical clustering by region (x-axis) and protein abundance (y-axis) shows that each region has a unique signature of postsynaptic proteome composition. (C) Neuroanatomical map of clusters in (B) showing proteome organization into forebrain and hindbrain structures: telencephalon, diencephalon and rhombencephalon.