Table 5.
Comparison of performance of DPM, NS and NSD w.r.t. various contributors studied in the present work.
| Contributors | DPM * | NS | NSD |
|---|---|---|---|
| Solubility (in HBSS pH 6.5 after 120 min) | 1.00 | 1.64 | 1.44 |
| Solubility (in medium 199 after 120 min) | 1.00 | 1.82 | 1.52 |
| Papp (apical-to-basolateral) | 1.00 | 3.30 | 2.35 |
| Papp (basolateral-to-apical) | 1.00 | 0.54 | 0.87 |
| Papp (mucosa-to-serosa) | 1.00 | 1.83 | 1.74 |
| Internalization (absorption-desorption study) | 1.00 | 3.62 | 2.79 |
| Mucoadhesion | 1.00 | 1.42 | 2.47 |
* Contribution of DPM has been assumed to be 1 for comparison of the performance of NS and NSD in various aspects.