Table 1.

Averages and Medians of EC₅₀ and T_1/2 Values in Insulin-Responsive Genes (IRGs) and Insulin-Responsive Metabolites (IRMs)

		Average	Median	p Value	Adjusted p Value	Mode
						< Threshold	> Threshold
EC50 (nM)	Upregulated IRGs	1.6	2.2	9.64 × 10−15	3.86 × 10−14	0.25	6.3
	Downregulated IRGs	0.25	0.16			0.10	1.0
	Increased IRMs	4.9	6.6	1.34 × 10−10	5.36 × 10−10	0.40	1.6
	Decreased IRMs	1.3	1.2			0.060	0.63
T1/2 (min)	Upregulated IRGs	68	50	9.82 × 10−5	3.93 × 10−4	45	120
	Downregulated IRGs	86	59			45	120
	Increased IRMs	56	68	1.90 × 10−3	7.60 × 10−3	0	105
	Decreased IRMs	18	11			15	60