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. 2018 Sep 19;10(9):511. doi: 10.3390/v10090511

Table 1.

Published animal models of Behçet’s disease (1979–2018).

Models and Symptoms Published Number of Papers
Environmental pollutants→Mucocutaneous lesions in miniature swine 1
Human 60 kD heat shock protein-derived peptide 336–351→Uveitis in rats 1
HLA-B51 Transgenic mice→Excessive function of peripheral blood neutrophils but no symptoms 1
Herpes simplex virus type 1→Oral, genital, and skin ulcers, eye involvement, arthritis, and intestinal involvement in ICR mice and C57BL/6 mice 26
Tropomyosin→Inflammation in the skin, joints, and eyes of Lewis rats 2
Retinal soluble antigen (S-Ag)→Uveitis in rats 1
Sera from seven NeuroBD patients→Reduced locomotor activity in rats 1