Table 4.
Correlation between serum biomarkers HbA1c, SBP, and DBP with serum creatinine and eGFR.
| Baseline Parameters | Serum Creatinine (mmHg) | eGFR (mL/min/1.73 m2) | ||
|---|---|---|---|---|
| Correlation, r | p-Value | Correlation, r | p-Value | |
| AGE (µg/mL) | 0.140 | 0.287 | −0.145 | 0.269 |
| sRAGE (pg/mL) | −0.199 | 0.121 | 0.185 | 0.151 |
| Nε-CML (ng/mL) | 0.31 | 0.015 * | −0.30 | 0.032 * |
| Cystatin C (ng/mL) | −0.238 | 0.061 | 0.164 | 0.199 |
| HbA1c (%) † | 0.116 | 0.369 | −0.049 | 0.704 |
| SBP (mmHg) ‡ | 0.182 | 0.153 | −0.126 | 0.325 |
| DBP (mmHg) ‡ | 0.086 | 0.504 | −0.017 | 0.893 |
Data controlled for HbA1c, SBP, DBP, and age. † Data controlled for SBP, DBP, age, and Nε-CML. ‡ Data controlled for HbA1c, age, and Nε-CML. * Significant at p < 0.05. AGE: Advanced Glycation Endproduct, sRAGE: soluble Receptor for AGE, Nε-CML: Nε-Carboxymethyllysine, HbA1c: Hemoglobin A1c, SBP: Systolic Blood Pressure, DBP: Diastolic Blood Pressure.