Table 1.
Relative HHV-8 infection burden in children, and proportion of HIV positive, HIV negative, and children with KS among the child population in Africa.
| African Region | Percentage of Children Infected with HHV-8 | Percentage of HIV Positive Children Infected with HHV-8 of All Children with HHV-8 | Percentage of HIV Negative Children Infected with HHV-8 of All Children with HHV-8 | Percentage of Children with KS and Infected with HHV-8 of All Children with HHV-8 | Chi-Square Value |
p-Value (Significant at p ≤ 0.05) |
|---|---|---|---|---|---|---|
| Southern | 31.4 (342/1092) | 52.6 (180/342) | 21.1 (72/342) | 26.3 (90/342) | 90.5 | < 0.0015 |
| Central | 49.5 (329/665) | No data | No data | No data | Not done | Not done |
| West | 11.4 (49/429) | 18.6 (80/429) | 81.3 (349/429) | No data | 128.8 | 0.0001 |
| East | 20.7 (945/4557) | No data | No data | 1.6 (15/945) | Not done | Not done |
| North | 43.3 (122/282) | No data | No data | 5.3 (15/282) | Not done | Not done |
| Chi-square value | 367.2 | 98.3 | 279.1 | 220.0 | 34.9 | 0.401 |
| p-value | < 0.00001 | - | - | - | - | - |
Data on children described in selected studies were summed up for each region and analysed. The percentages of HIV positive children, HIV negative children, and children with KS are calculated based on the total number of children with HHV-8 pooled from the extracted studies in the different African regions. Data from North Africa were not sufficient for meaningful comparable analysis and were omitted.