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. 2016 Dec 17;13(6):612–621. doi: 10.1007/s13770-016-8111-8

Current advances in three-dimensional tissue/organ printing

Jeong Hun Park 1, Jinah Jang 1, Jung-Seob Lee 1, Dong-Woo Cho 1,2,✉
PMCID: PMC6170865  PMID: 30603443

Abstract

Three-dimensional (3D) tissue/organ printing is a major aspect of recent innovation in the field of tissue engineering and regenerative medicine. 3D tissue/organ printing aims to create 3D living tissue/organ analogues, and have evolved along with advances in 3D printing techniques. A diverse range of computer-aided 3D printing techniques have been applied to dispose living cells together with biomaterials and supporting biochemical factors within pre-designed 3D tissue/organ analogues. Recent developments in printable biomaterials, such as decellularized extracellular matrix bio-inks have enabled improvements in the functionality of the resulting 3D tissue/organ analogues. Here, we provide an overview of the 3D printing techniques and biomaterials that have been used, including the development of 3D tissue/organ analogues. In addition, in vitro models are described, and future perspectives in 3D tissue/organ printing are identified.

Key Words: 3D tissue/organ printing, Bio-ink, 3D tissue/organ analogue, In vitro tissue model, Tissue engineering and regenerative medicine

Footnotes

These authors contributed equally to this work.

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