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. 2018 Jul 24;32(5):425–440. doi: 10.1007/s40259-018-0295-0

Table 3.

Monoclonal antibodies for subcutaneous administration in oncology [64, 65]

Molecule Brand name (originator) Dosing frequency Injection volume Device
Anti-HER2 mAb
 Trastuzumab Herceptin (Roche)a,b q3w 5 ml Vial and syringe
Anti-CD20 mAb
 Rituximab MabThera/Rituxan Hycela (Roche)a,b q3w–q3mc 11.7–13.4 ml Vial and syringe

CD cluster of differentiation, HER human epidermal growth factor receptor, mAb monoclonal antibody, qXw once every X weeks, qXm once every X months

aSubcutaneous and intravenous formulation marketed

bSubcutaneous formulation contains recombinant human hyaluronidase (rHuPH20)

cDepending on the type of follicular lymphoma