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. 2018 Oct 11;6:e5694. doi: 10.7717/peerj.5694

Table 3. Cytotoxicity of the extracts of F. deltoidea leaves against WRL68 cells.

Sample Extract/fraction Incubation
24 hr (IC50 - µg/ml) 48 hr (IC50 - µg/ml) 72 hr (IC50 - µg/ml)
FDS Crude N/D N/D N/D
Water fraction N/D N/D N/D
Ethyl acetate fraction N/D N/D N/D
FDM Crude N/D N/D N/D
Water fraction N/D N/D N/D
Ethyl acetate fraction N/D N/D N/D
FDB Crude N/D N/D 347.67 ± 2.52
Water fraction 378.3 ± 5.51 306.7 ± 7.37 224 ± 21.17
Ethyl acetate fraction N/D N/D N/D

Notes.

The experiment was conducted in a 96-well plate, each in triplicate. Cells were allowed to attach for 24 h after seeding. WRL68 cells were treated with various concentrations of the extracts of F.deltoidea crude extracts and fractions for 24, 48 and 72 h.

Results were expressed as means ± S.D. (n = 3).

IC50 = concentration of plant extracts (μ g/ml) that inhibited 50% of the cells.

N/D, no inhibition detected