Xerostomia and hyposalivation in orthogeriatric patients with fall history and impact on oral health-related quality of life

Abstract

Purpose

Falls are a common cause of morbidity and mortality in older people, and identification of risk indicators and risk factors to prevent falling is essential. Dry mouth (xerostomia and hyposalivation) can exacerbate conditions known to be fall risk indicators, such as nutritional status and sarcopenia. But there is little evidence regarding whether it is an independent risk factor for falling. We explored xerostomia prevalence and intensity and objective salivation rates in hospitalized geriatric patients to determine whether they were associated with an increased risk of falling.

Patients and methods

Hospitalized geriatric patients with and without a fall history were compared. We investigated several oral health issues including xerostomia, stimulated and unstimulated salivation rates, total number of teeth and prosthetics, periodontal status, and oral health-related quality of life.

Results

Forty patients were included, 28 in the fall history group and 12 in the control group. All patients had oral health issues that impacted on their oral health-related quality of life. However, there were no significant differences between the groups, including xerostomia and hyposalivation, apart from increased dysphagia and less flavor in food in patients with a fall history.

Conclusion

Dry mouth does not appear to be an independent risk factor for falling in this population, but oral health was impaired. Thus, it is important that dentists and geriatricians are aware of and investigate these conditions in their patients and that appropriate action is taken to reduce the consequences of impaired oral health, including a potential reduction in falls.

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Introduction

The prevalence of falls increases with age, affecting 28%–35% of older people globally every year.¹ Falls are the most common cause of trauma and trauma-related deaths among older people,² and morbidity and mortality after a fall are correlated with frailty,³ while age constitutes the strongest predictor of mortality.⁴ In 40%–60% of cases, falls are associated with major lacerations, fractures, or traumatic brain injuries,⁵ resulting in reduced physical activity, deconditioning, functional decline, impaired ability to perform daily activities, social isolation, reduced quality of life, depression, increased risk of subsequent falls, and institutionalization.^6–9 Nearly 95% of all hip fractures are caused by falls, 95% of patients with hip fractures are discharged to nursing homes, and 20% of patients with a hip fracture die within a year.¹⁰

Therefore, it is important to identify risk indicators and factors to better prevent falls among older people. In the community, these include previous falls, demographic characteristics, health habits, pain, chronic diseases, medication use, disabilities, and sarcopenia.^11–13 In light of the shift toward interdisciplinary scientific approaches to patient management, certain risk factors are of importance not only for geriatricians and gerontologists but also for dentists. In particular, polypharmacy (often defined as the use of four or more drugs) is commonly described as a risk factor in patients who fall.¹⁴ Furthermore, the use of specific drugs (eg, antidepressants, sedatives and hypnotics, neuroleptics and antipsychotics, antihypertensives, and anticonvulsants) have been linked to an increased risk of falls.^15–17 Yet although most of these prescription medicines have dry mouth as a side effect and impact on oral health,¹⁸ it is surprising that dry mouth and other oral health issues are not yet regularly listed in the long list of risk factors for falls. As both nutritional status and sarcopenia are risk factors for falls among geriatric patients^19,20 – and dry mouth is associated with dysphagia, taste disturbances, and often reduced and changed nutritional intake and therefore sarcopenia^21,22 – we assume that subjective and objective dry mouth might also serve as independent risk factors or at least risk indicators. Xerostomia (abnormal subjective dryness of the mouth due to insufficient secretions) – in contrast to hyposalivation (the objective finding of decreased salivary production, defined as a whole stimulated salivary rate of <0.5–0.7 mL/min^23,24)²⁵ – defines the dry mouth experienced after use of medications.²⁶ There is evidence to suggest that a 50% decrease in salivary flow will result in xerostomia; however, xerostomia may also occur in patients with normal salivary flow rates.²⁷ Salivary gland hypofunction disrupts the normal homeostasis of the oral cavity, causing a range of oral diseases including dental caries, candidiasis, taste disturbances, and difficulties with chewing, swallowing, and speaking.²⁸

The correct definition of dry mouth as a risk factor for falls is challenging, as it is difficult to discriminate between the high number of causes of dry mouth problems factors such as Sjögrens’s syndrome, age, gender, and head and neck radiotherapy.^29,30 Also it is difficult to discriminate between possible side effects of medications and the underlying diseases for which these medications have been described and their influence on dry mouth conditions. In addition, dry mouth independently shows high prevalence among the elderly.³¹ Furthermore, our own recent findings have shown that older (Parkinson’s disease) patients tend to underestimate their dry mouth conditions and rarely report them to their dentists.³²

In the literature, only limited data regarding the association between xerostomia, hyposalivation, and fall prevalence in orthogeriatric patients with fall history, as well as how these patients perceive their xerostomia, are available. Ortho-geriatric patients are elderly patients (here inpatients) in need of an interdisciplinary orthopedic and geriatric approach based on a concept of orthogeriatric co-management.³³ Additionally, it is not clear whether orthogeriatric patients with fall history suffer from impaired oral health-related quality of life (OHrQoL) and the impact of their dry mouth conditions. Therefore, we conducted an interdisciplinary clinical comparison between a group of well-characterized hospitalized orthogeriatric patients with a fall history and a group of hospitalized geriatric patients without a fall history. Our aim was to explore xerostomia prevalence and intensity as well as objective salivation rates in the two groups. In addition, the OHrQoL was investigated, as was the association between subjective and objective dry mouth and fall prevalence. We hypothesized that patients with fall history suffer more often from xerostomia and hyposalivation compared with non-fallers, as well as impaired OHrQoL influenced by their dry mouth conditions.

Patients and methods

Participants

Geriatric patients either admitted from the community to the orthogeriatric department with a fall and trauma history or admitted to the geriatric care unit without a fall history (controls) were included in the study. All participants were recruited from the urban hospital Evangelisches Krankenhaus Kalk, Germany, either from the department of traumatology, orthopedics, and orthogeriatrics (ATZ) or the department of geriatric medicine. Patients were included if they were older than 70 years, were able to give written informed consent, and were hospitalized at the ATZ. All eligible participants who were willing to participate were included in the study from December 2017 until April 2018. None of the participants suffered from Sjögren’s syndrome, had or have ever had head and neck malignancies, nor radiation therapy in the head and neck region.

Parameters assessed

Clinical characteristic/medical history

Age, comorbidities, dependency level, nutritional status via the Mini Nutritional Assessment,³⁴ and prescribed medications were documented, based on the medical records of the ATZ. Based on the recommendations of the European Working Group on Sarcopenia in Older people, hand grip strength measured by a dynamometer (DHD-1 Digital Hand Dynamometer, Saehan Company, South Korea) was used as marker for sarcopenia.³⁵

Questionnaires

All questionnaires were completed in a quiet room without help or interference where possible. If participants asked for help with reading or writing, one dental nurse (PS) was present to assist. Participants could take as much time as they needed. The questionnaires were finalized and collected before the clinical examinations. The questionnaires included the OHrQoL via the German version of the Oral Health Impact Profile (OHIPG-14)³⁶ and the Xerostomia Questionnaire (XQ).³⁷

Xerostomia

Self-assessed xerostomia was classified by answering “yes” or “no.” Additionally, a visual analog scale (VAS) score (0–10 cm) was obtained from the participants, where they rated their subjective burden from 0 (completely normal saliva) to 10 (no saliva at all).

German version of the OHIPG-14

Oral health was measured with the OHIPG-14 questionnaire.³⁶ The questions of the OHIPG-14 monitor pain, physical, psychological, and social limitations, and disabilities on a 5-level scale ranging from never (score 0), hardly ever (1), occasionally (2), fairly often (3) to always (4). The results are expressed as the sum of the scores for the 14 questions (maximum 56).

XQ

The XQ consists of three parts. Patients were asked to estimate the degree (grade 0–3) of oral dryness, pain, taste loss, and dysphagia. In addition, patients answered 15 questions regarding the perceived impact of xerostomia on their quality of life. For each question, participants encircled a number from 1 to 5, reflecting the measure of agreement with the statement.³⁷

Oral health characteristics

The total number of teeth and the prosthetic situation were described and the periodontal status was documented by the community periodontal index of treatment needs.³⁸ The root caries index (RCI) was graded on a scale from RC1 (hard surface) to RC5 (soft surface),³⁹ and oral hygiene was documented by the oral hygiene index (OHI).⁴⁰

Unstimulated salivation rates

All saliva collections took place between 9 and 11 am in a quiet room of the orthogeriatric ward and were performed by the same examiner (PS). Participants were asked to relax for a couple of minutes before saliva collection. They were sitting in an ordinary chair bent forward and were asked to hold their mouth open and remain still, letting the saliva drip into a disposable cup held to the lower lips for 5 minutes. Volumes (mL) were determined using luer slip syringes (BD Discardit II; Becton, Dickinson and Company, Franklin Lakes, NJ, USA). Saliva produced at a rate <0.2 mL/min was defined as objective hyposalivation.

Stimulated salivation rates

The participants did not consume any food or drinks 1 hour prior to the examination and did not brush their teeth during this time. Stimulated salivation rates were measured 1 hour minimum after the unstimulated salivation rates took place. The clinical collection of chewing-stimulated whole saliva samples has been outlined in detail elsewhere.^41,42 In brief, stimulated saliva sampling was started by flushing in tap water followed by chewing on paraffin wax (Ivodent Vivadent AG, Liechtenstein, Ellwangen, Deutschland) (1 g) for 30 seconds. Subsequently, participants were instructed to spit continuously for 5 minutes in a sterile plastic cup to obtain the rate (mL/min), and during the last few seconds of the 5 minutes, the resting amount of saliva also was collected. Volumes (mL) were determined using luer slip syringes (BD Discardit II; Becton, Dickinson and Company). Saliva produced at a rate <0.7 mL/min was defined as objective hyposalivation.⁴³

Sample size calculation

No classic sample size calculation was performed. Because of the pilot nature of the study, we defined a realistic timespan for recruiting; therefore, all participants willing to participate were consecutively included between December 2017 and April 2018. A post-study sample size calculation for future studies with the results of the unstimulated salivation rates was performed.

Ethics

The University of Cologne local ethics review board (study number: 17-389, date of issue: 11/27/2017) granted approval for the study. The study was registered at the Deutsches Register für Klinische Studien (German Registry of Clinical Trials) with the study number DRKS00013230.

Statistical analysis

Continuous variables are summarized as mean (SD) values, contingent on distributional characteristics. Qualitative variables are described by count and percentage. The correlation of clinical measures with VAS values, OHIPG-14 total scores, and objective saliva amounts was calculated according to Spearman; only coefficients ≥0.3 are reported. Distributions of paired and unpaired data were compared by rank-based methods, that is, Wilcoxon signed-rank test and Mann–Whitney U-test, respectively. ORs were calculated for stimulated and unstimulated salivation rates among study participants with and without fall history. All calculations were done with SPSS Statistics 24 (IBM Corporation, Armonk, NY, USA). Data were entered twice and reconciled in case of inconsistencies. P-values <0.05 were considered to indicate statistical significance (comparison-wise type I error control).

Results

Clinical characteristics

Twenty-eight geriatric trauma patients with a fall history and 12 controls without a fall history provided written informed consent and completed the study. Of the patients with fall history, 73% were female and the mean age was 83 (SD: 7) years. All participants had regular medical and dental health insurance. There were no significant differences between patients with a fall history and controls regarding the number of remaining teeth (P=0.082), the RCI (P=0.391), and OHI (P=0.140) (Table 1). Overall, 64% of participants suffered from periodontitis, with no significant differences between the two groups.

Table 1.

Clinical characteristics

	Study participants, n (%a)	Fall history group, n (%)	Controls, n (%)	P-value
Gender
Female	29 (73)	20 (72)	9 (75)	0.822
Total prostheses
Upper and lower jaw	10 (25)	9 (32)	1 (8)
Lower jaw only	2 (5)	2 (7)	0
Upper jaw only	6 (15)	3 (11)	3 (25)
Permanent dentures	20 (50)	12 (43)	8 (67)	0.176
Xerostomia	38 (95)	26 (93)	12 (100)	0.355
Periodontitis	21 (64)	14 (67)	7 (59)	0.645
Risk for malnutrition (MNA 8–11 points)	9 (39)	7 (39)	2 (40)
Malnutrition (MNA <8 points)	12 (52)	9 (50)	3 (60)
	Mean (SD)	Mean (SD)	Mean (SD)
Age (years)	83 (7)	84 (7)	81 (6)	0.270
Total number of APIs	10 (4)	11 (3)	8 (4)	0.092
Total number of teeth	11 (10)	9 (10)	15 (8)	0.082
Oral Hygiene Index	0.5 (0.7)	0.7 (0.8)	1.9 (0.3)	0.140
Root Caries Index	2.1 (1.6)	2.3 (1.6)	1.7 (1.6)	0.391
MNA	7 (3)	7 (3)	7 (3)	0.816
Hand grip, right hand (kg)	16 (7)	16 (7)	15 (7)	0.744
Hand grip, left hand (kg)	15 (7)	15 (7)	14 (7)	0.619

Notes: Statistical significance <0.05;

^a% defined as valid percent of total patients in the clinic at the beginning of the data collection period. Hand grip measured by hydraulic hand grip dynamometer.

Abbreviations: APIs, active pharmaceutical ingredients; MNA, Mini Nutritional Assessment.

Xerostomia

The mean xerostomia VAS score of orthogeriatric patients with fall history was 5.4 (SD: 2.7) vs 4.9 (SD: 2.4) among controls (P=0.563). The values reported on the VAS did not correlate with increasing age, gender, RCI, or OHI, but did show a correlation with subjective dysphagia (r=0.451, P=0.016). Regarding ORs, the combination between “no xerostomia” and “non-faller” was missing; therefore, no OR could be calculated.

Salivation rates

Sixty-four percent of patients with fall history suffered from objective hyposalivation regarding the unstimulated salivation rates and 75% regarding the stimulated salivation rates, 93% reported to suffer from xerostomia. There was no difference between stimulated (P=0.883) or unstimulated (P=0.492) salivation rates between patients with a fall history and controls, with a mean stimulated salivation rate of 0.4 mL/min (SD: 0.4) in both the groups. Regarding unstimulated salivation rates, patients with a fall history showed a mean rate of 0.3 mL/min (SD: 0.5) vs 0.2 mL/min (SD: 0.2) in controls (P=0.492). The whole stimulated salivation rates of patients with a fall history correlated with age (r=0.351, P=0.067) and xerostomia VAS (r=0.395, P=0.037). Unstimulated salivation rates correlated with subjective dysphagia (r=0.378, P=0.047) and xerostomia VAS (r=0.432, P=0.022) in this group. ORs were calculated for hyposalivation for stimulated salivation rates (<0.7 mL/min): (OR =1.50 [95% CI: 0.34, 6.55], P=0.590); and hyposalivation for unstimulated salivation rates (<0.2 mL/min): (OR =1.29 [95% CI: 0.32, 5.13], P=0.722). In addition, a post hoc power analysis was performed. Taking into account the results regarding the unstimulated salivation rates (defined as <0.2 mL/min), power for the reported effect and sample size is 12.2%. In proof of delivery of this effect with a power of at least 80%, a sample size of 209 participants per group (418 cases) would be necessary in future studies.

XQ

Regarding the XQ Part 1, only dysphagia items showed higher mean values among patients with a fall history than controls (P=0.013). Detailed results are shown in Table 2. Regarding the XQ quality of life questions, almost all items showed elevated values, but no statistically significant differences were seen between groups (Table 3).

Table 2.

Results of the Xerostomia Questionnaire Part 1 items for patients with fall history compared with controls

	Fall history, % (n)	Controls, % (n)	P-value
Oral dryness			0.922
No oral dryness	18 (5)	25 (3)
Now and then, partial	54 (15)	42 (5)
Always, partial	14 (4)	17 (2)
Completely dry, disturbing	14 (4)	17 (2)
Oral pain			0.961
No pain	68 (19)	83 (10)
Seldom, minimal	32 (9)	–
Always, strong	–	17 (2)
Unbearable	–	–
Taste loss			0.202
No change	86 (24)	92 (11)
Seldom, minimal	4 (1)	8 (1)
Now and then, considerable	4 (1)	–
Always	7 (2)	–
Dysphagia			0.013*
No swallowing problems	75 (21)	100 (12)
Solid food	14 (4)	–
Soft food	7 (2)	–
Liquids	4 (1)	–

Note:

^*Statistical significance <0.05.

Table 3.

Results of the Xerostomia Questionnaire quality of life items for patients with fall history compared with controls

My dry mouth…	Fall patients, mean (SD)	Controls, mean (SD)	P-value
Restricts the amount and type of food I eat	0.4 (0.8)	0.6 (0.9)	0.617
Gives me an uncomfortable feeling in the mouth	2.3 (1.5)	1.6 (1.8)	0.233
Makes me worry	1.2 (1.4)	0.8 (1.3)	0.427
Restricts my social life	0.2 (0.5)	0.8 (1.2)	0.140
Makes it awkward to eat in front of other people	0.2 (0.7)	0.6 (1.0)	0.260
Makes it difficult to speak to other people	0.5 (0.9)	1.1 (1.6)	0.262
Is the cause of considerable tension	0.1 (0.4)	0.6 (1.1)	0.161
Makes me worry about the look of my teeth and mouth	0.3 (0.7)	0.2 (0.4)	0.502
Makes me feel depressed	0.0 (0.2)	0.4 (0.8)	0.127
Restricts me in my daily activities	0.3 (0.5)	0.6 (0.9)	0.250
Troubles my intimate relation	0.0 (0.2)	0 (0)	0.327
Gives my food less or a different taste	0.7 (1.2)	0.3 (0.9)	0.314
Diminishes my will to live	0 (0)	0 (0)
Invades every aspect of my life	0.0 (0.2)	0.1 (0.3)	0.607
Cannot stay like this for the rest of my life	2.3 (1.7)	2.3 (1.8)	0.908

Note: Statistical significance <0.05.

Oral Health Impact Profile

The mean OHIPG-14 total score was 10.0 (SD: 8.0) in patients with a fall history vs 7.8 (SD: 9.8) in controls, without a difference between the groups (P=0.510) (Table 4). In addition, none of the OHIPG-14 sub-items differed between patients with a fall history and controls, apart from less flavor in food which was reported more often by patients with a fall history (P=0.006). Taste disturbances (r=0.5, P=0.006), suffering from periodontitis (r=0.386, P=0.084), and the OHI (r=0.306, P=0.202) correlated with the OHIPG-14 total scores among patients with a fall history.

Table 4.

German Oral Health Impact Profile 14 items in patients with fall history compared with controls

OHIPG-14 item	Fall history Mean (SD)	Controls Mean (SD)	P-value
1. Trouble pronouncing words	0.6 (1.0)	0.3 (0.6)	0.132
2. Less flavor in food	0.6 (1.1)	0 (0)	0.006*
3. Life less satisfying	1.6 (1.4)	1.0 (1.0)	0.141
4. Unable to work	0.9 (1.1)	0.4 (1.0)	0.197
5. Tense feeling	1.0 (1.3)	0.6 (1.4)	0.428
6. Interrupt meals	0.6 (1.2)	0.3 (0.9)	0.298
7. Uncomfortable to eat	0.6 (1.0)	0.4 (1.0)	0.585
8. Upset	0.6 (1.1)	0.8 (1.4)	0.679
9. Trouble getting on with others	0.9 (1.1)	1.1 (1.2)	0.632
10. Unable to function	0.7 (1.1)	0.9 (1.5)	0.679
11. Being embarrassed	0.3 (0.6)	0.4 (0.7)	0.463
12. Difficulty chewing	0.8 (1.1)	0.9 (1.3)	0.767
13. Pain in oral area	0.4 (0.9)	0.6 (1.4)	0.725
14. Uncertainty	0.4 (0.8)	0.3 (0.6)	0.578
Total score	10.0 (8.0)	7.8 (9.8)	0.510

Note:

^*Statistical significance <0.05.

Abbreviation: OHIPG, German version of the Oral Health Impact Profile.

Discussion

Orthogeriatric patients in our study suffered from xerostomia and hyposalivation with objective measurements for hyposalivation that were below the defined rates for whole stimulated saliva.^23,24 They also reported elevated subjective xerostomia VAS values that were comparable to those from other populations, for example, patients with head and neck cancer³⁷ which correlated with subjective dysphagia. However, no differences in subjective and objective dry mouth conditions were observed between the study groups. Therefore, contrary to our hypotheses, we could not define xerostomia and hyposalivation as independent risk factors for falling among geriatric patients. However, our study shows that orthogeriatric patients with and without fall history have impaired oral health in terms of missing remaining teeth, root caries, subjective dysphagia problems, disturbed flavor in food, and oral hygiene impairment. Furthermore, even though there were no differences between groups regarding OHrQoL, it was impaired in all participants.

Hyposalivation leads to impaired oral health, including a microbial shift that causes caries, periodontitis, loss of teeth, impaired masticatory function, and a higher risk of aspiration pneumonia among elderly patients.⁴⁴ In our study, oral health was impaired among geriatric patients, albeit independently from their fall history. These indicators of impaired oral health interact with other individual and environmental risk factors, leading to faster decline, faster development of frailty, and therefore a greater risk of falls. Fewer functional teeth may lead to impaired masticatory function⁴⁵ combined with oral pain, infection, root caries, and dysphagia, resulting in impaired nutritional status with weight loss,⁴⁶ a higher risk for orthostatic hypotension,⁴⁷ and diverse hypovitaminoses such as vitamin D deficiency^48,49 – all risk factors for frailty, and therefore associated with a higher risk for occurring falls. Dysphagia was reported more often in our fall patients compared with controls. Oropharyngeal dysphagia has been proposed as a geriatric syndrome, since it has high prevalence in older persons, is combined with other symptoms such as coughing or repetitive swallowing or aspiration,⁵⁰ with high prevalence in older neurological patients,⁵¹ and shows a close interrelation with malnutrition.⁵² Less flavor in food was also reported significantly more often among patients with fall history than controls. Other groups have shown that hospitalized patients were less able to taste citric acid compared to controls.⁵³ Gustatory impairment may reduce appetite and again lead to inadequate dietary intake. Since diverse treatment options such as the use of flavor-enhanced foods or compensatory nutritional food are available, and logopedic therapy has several approaches to improve dysphagia problems, dentists should be aware of these problems among their patients.

Even though we were unable to show that dry mouth is an independent risk factor for the incidence of falling among this population, our data provide evidence that the complex and very individual overall combination of diverse oral health issues (with dry mouth being just one among many others) might instead be the risk factor. Accordingly, easy diagnostic tools need to be implemented in daily clinical practice for both dentists and general practitioners, since we strongly encourage both to become aware of dry mouth in their patients. Although there are currently few socially acceptable and satisfactory therapeutic approaches to increase salivation rates independent from the underlying causes, several symptomatic treatments and preventive approaches are available to reduce the consequences of hyposalivation.⁵⁴

The OHrQoL in our population was impaired in patients with a fall history and in controls, but values were not outstandingly high compared to other groups. However, relatively non-symptomatic chronic dental problems might not have the same kind of impact on OHrQoL as acute pain resulting from deep carious lesions or acute infections, for example. Since subjective oral pain was reported to be very low among our population, we assume that there were no such conditions in our study population. In addition, pain perception of the elderly seems to decrease with age,⁵⁵ as does self-perception and self-awareness regarding oral health not only among the elderly but also among their caregivers.⁵⁶ Furthermore, reported xerostomia, oral pain, taste loss, and dysphagia seem to represent rather minor problems in the self-perception of geriatric patients. This highlights the need for specific investigations and early intervention of these symptoms to initiate need-related intervention plans and thus potentially reduce the risk of falling.

We have investigated oral health parameters among a vulnerable population of frail geriatric patients who represent a group that is often not the focus of practicing dentists and researchers. Since maintenance of good oral health is essential in this group, our study has addressed this topic. Geriatric patients living in the community might often not be able to find their way to dentists, and ways of bringing dental medical care to this group need to be further addressed in the future.⁵⁷ Furthermore, decreased self-awareness of oral symptoms has been described among other populations, that is, for swallowing dysfunction⁵⁰ or dry mouth among Parkinson’s disease patients.⁵⁸ Our study setting, with a dentist examining in a short dental check-up, could serve as an example for regularly providing dental check-ups in a geriatric hospital setting, providing screening possibilities for older people living in the community.

The main limitation of our study is the low number of recruited controls among this vulnerable group in the predefined timespan of 5 months. This may be explained by the infrastructure of the study hospital, with a higher turnover of fall patients who were hospitalized for a shorter time than geriatric patients admitted to the hospital for other reasons. An interdisciplinary approach that includes the field of dentistry is required to better identify and define the risk factors for falling, enabling dentists, geriatricians, and general practitioners to prevent such events in geriatric patients in the community and potentially reduce the risk of falling.

Conclusion

Orthogeriatric patients with a fall history suffer from an impaired oral health, dysphagia, taste disturbances, xerostomia, and hyposalivation, and an impaired OHrQoL, as do orthogeriatric patients without fall history. Although oral symptoms are seemingly less important in the self-perception of geriatric patients, their combined impact may increase the risk of falls and thus it is essential that dentists and geriatricians investigate, prevent, and treat these conditions.