Table 1.

Clinical characteristics of 17 renal transplant patients at the time of diagnosis of Pneumocystis pneumonia (PCP).

Variable	N (%) or median (range)
Male/female	9 / 8 (53%/47%)
Median age, years (range)	40 (24-63)
Kidney transplant type
Living donor	1 (6%)
Deceased donor	14 (82.3%)
Kidney-pancreas	2 (11.7%)
Second transplant	3 (17.6%)
Opportunistic infections and other co-morbidities
Cytomegalovirus within 6 months before the diagnosis of PCP	3 (17.6%)
Systemic lupus erythematosus (SLE)	2 (11.8%)
Diabetes mellitus	7 (41.2%)
Change or modulation of immunosuppression within 6 months before the diagnosis of PCP	4 (23.5%)
Rejection within 6 months before diagnosis of PCP	5 (29.4%)
Immunosuppressive drugs
Calcineurin inhibitor	13 (76.4%)
Corticosteroid	17 (100%)
Azathioprine	3 (17.6%)
Mycophenolate preparation	13 (76.4%)
Sirolimus	1 (5.9%)
Median time, months, from transplant to diagnosis of PCP	30 (4-75)
Mean duration, days, of respiratory symptoms	16 (1-86)
Cough	15 (88.2%)
Dyspnea	16 (94.1%)
Fever	13 (76.5%)
Diagnosis
Direct detection by toluidine blue O staining in bronchoalveolar lavage	0 (0%)
Transbronchial biopsy	9 (52.9%)
Open lung biopsy	8 (47.1%)
ICU admission	16 (94.1%)
Intubation	12 (70.6%)
Death	6 (35.3%)

ICU = intensive care unit.