Age-adjusted incidence in DCIS and metastatic breast cancer among women
20–39 years old by age groups, SEER 1975–2015.
DCIS: ductal carcinoma in situ.
A. 20–29 years old. B. 30–39 years old.
Annual percentage changes (APC) and p values:
Among women 20–29 years old
DCIS: 1975–2015 APC 2.8 p<0.001
Metastatic: 1975–2015 APC 3.8 p<0.001
Among women 30–39 years old
DCIS: 1975–1989 APC 11.1, p<0.001; 1989–2005
APC 2.5, p=0.001; 2005–2015 APC −1.9, p=0.14. 1975–1989 vs.
1989–2005 p<0.001. 1989–2005 vs. 2005–2015
p=0.005)
Metastatic: 1975–1995 APC 0.8, p=0.22; 1995–2015 APC
3.9, p<0.001. P value for the difference <0.001