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(A) Meso-2 cells were treated with 3 µg of control- or TG2-siRNA and after 48 h extracts were prepared to monitored TG2 level. (B–D) TG2 knockdown in Meso-2 cells reduces spheroid number and size, matrigel invasion and migration. The values are mean ± SEM and asterisks indicate a significant change compared to control, n = 3, p < 0.05. Bars = 50 microns in all panels.
