Table 4.
Comparisons of retinal thickness measures at baseline (in µm)a
| African Americans | Caucasian Americans | African Americans versus Caucasian Americans | ||
|---|---|---|---|---|
| Mean (SD) µm | Mean (SD) µm | P-valuea | P-valueb | |
| Healthy controls | n = 31 | n = 61 | ||
| p-RNFL | 97.39 (8.36) | 93.10 (10.37) | 0.039 | NA |
| T-quadrant p-RNFL | 66.21 (10.96) | 64.78 (11.04) | 0.580 | NA |
| GCIP | 75.35 (4.41) | 77.03 (5.36) | 0.110 | NA |
| INL | 43.12 (2.65) | 45.57 (2.67) | <0.001 | NA |
| ONL | 65.78 (6.65) | 68.79 (5.32) | 0.015 | NA |
| AMT | 306.79 (14.48) | 314.54 (12.80) | 0.007 | NA |
| Multiple sclerosis | n = 116 | n = 116 | ||
| p-RNFL | 85.60 (15.28) | 87.87 (12.70) | 0.186 | 0.216 |
| T-quadrant p-RNFL | 51.13 (12.17) | 56.52 (14.16) | 0.001 | 0.001 |
| GCIP | 67.86 (10.57) | 71.15 (8.71) | 0.004 | 0.004 |
| INL | 44.70 (3.55) | 45.19 (3.12) | 0.194 | 0.183 |
| ONL | 66.98 (5.45) | 68.07 (6.42) | 0.145 | 0.152 |
| AMT | 297.86 (18.82) | 304.98 (18.45) | 0.002 | 0.002 |
aDerived from models adjusted for sex and baseline age.
bDerived from models adjusted for sex, age at baseline, disease duration and history optic neuritis.
AMT = average macular thickness; NA = not applicable; T-quadrant = temporal quadrant. Bold values indicate statistical significance (P < 0.05).