Table 2.
Baseline cognitive testing
| Measure | Control | CADASIL | P-value | CADASIL No apathy | CADASIL Apathy | P-value |
|---|---|---|---|---|---|---|
| ACE | 96.6 ± 2.4 | 92.3 ± 5.3 | 0.003 | 94.9 ± 2.4 | 90.3 ± 6.1 | 0.064 |
| Digit Span | 6.1 ± 0.8 | 6.1 ± 0.8 | 6 ± 0.8 | 0.74 | ||
| Design Fluency | 30.7 ± 6.6 | 25.4 ± 9.3 | 0.053 | 28.6 ± 5.4 | 23 ± 11.0 | 0.20 |
| TMT − Aa | N/A | 30 ± 15.7 | N/A | 22.8 ± 8.0 | 35.8 ± 18.2 | 0.08 |
| TMT − Ba | N/A | 86.7 ± 54.3 | N/A | 65 ± 27.1 | 104.1 ± 65.1 | 0.13 |
| TMT − B-Aa | N/A | 56.7 ± 41.4 | N/A | 42.3 ± 25.2 | 68.3 ± 49 | 0.19 |
Values are mean ± SE. Values in bold represent P < 0.05. ACE = Addenbrooke’s Cognitive Examination III; TMT = Trail Making Task.
aData for the Trail Making Task was missing for one participant.