Table 2.
Characteristic | No hypertension* (N = 2,617) |
Newly classified with hypertension† (N=618) |
Hypertension based on traditional criteria‡ (N = 2,145) |
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---|---|---|---|---|---|---|
N | Weighted mean or percent (95% CI) | N | Weighted mean or percent (95% CI) | N | Weighted mean or percent (95% CI) | |
Demographic variables | ||||||
Age (years) | 38.9 (38.0, 39.8) | 46.4 (44.5, 48.3) | 60.0 (59.2, 60.9) | |||
Women | 1,455 | 55 (52, 57) | 255 | 43 (37, 49) | 1,085 | 50 (47, 53) |
Race/ethnicity | ||||||
White, non-Hispanic | 1,097 | 63 (56, 71) | 249 | 63 (55, 71) | 966 | 71 (64, 77) |
Black, non-Hispanic | 413 | 10 (6, 13) | 135 | 13 (9, 17) | 561 | 14 (10, 18) |
Asian, non-Hispanic | 358 | 6 (4, 8) | 63 | 5 (3, 6) | 190 | 4 (3, 5) |
Hispanic | 655 | 18 (12, 24) | 148 | 16 (11, 21) | 388 | 10 (5, 14) |
Medical history | ||||||
Diabetes | 112 | 3.4 (2.6, 4.1) | 59 | 8 (5, 11) | 611 | 25 (23, 27) |
CVD | 60 | 2 (1, 3) | 19 | 3 (1, 4) | 438 | 19 (17, 21) |
Atherosclerotic CVD risk (%), mean | 2.6 (2.3, 2.9) | 5.5 (4.7, 6.2) | 16.5 (15.6, 17.4) | |||
ASCVD> 10% | 167 | 6 (4, 7) | 118 | 18 (14, 23) | 1,191 | 55 (51, 59) |
Medications | ||||||
Antihypertensive medications | 0 | 0 | 0 | 0 | 1,723 | 80 (77, 84) |
Lipid-lowering medications | 143 | 6 (5, 8) | 53 | 10 (6, 14) | 931 | 45 (41, 48) |
Statins | 127 | 6 (4, 7) | 48 | 9 (5, 12) | 867 | 41 (37, 45) |
Fibrates | 15 | 0.5 (0.1, 0.9) | 4 | 1.5 (0, 3.2 | 74 | 4.0 (2.5, 5.4) |
Aspirin | 1 | 0.02 (0, 0.07) | 2 | 0.4 (0, 1.0) | 48 | 1.5 (0.9, 2.0) |
Physical examination | ||||||
BMI (kg/m2), mean | 27.5 (27.1, 27.9) | 30.3 (29.5, 31.2) | 31.0 (30.6, 31.4) | |||
Systolic BP | 112.2 (111.7, 112.6) | 128.8 (127.8, 129.7)§ | 133.4 (131.8, 135.0)║ | |||
Diastolic BP | 66.7 (65.9, 67.5) | 77.7 (76.7, 78.8)§ | 71.6 (70.5, 72.7)║ | |||
Laboratory data | ||||||
eGFR (mL/min/1.73 m2), mean | 101 (99, 103) | 96 (94, 98) | 81 (80, 83) | |||
eGFR < 60 | 46 | 1.7 (1.0, 2.3) | 10 | 1.7 (0.5, 3.0) | 392 | 18 (16, 20) |
Cell contents are N, mean (95% CI), or proportion (%) (95% CI).
Abbreviations: CVD, cardiovascular disease; ASCVD, atherosclerotic cardiovascular disease; BMI, body mass index; eGFR, estimated glomerular filtration rate.
No hypertension was defined as SBP <130 mmHg, DBP<80 mmHg, and no treatment with antihypertensive medication.
Newly classified with hypertension was defined as SBP≥130 mmHg or DBP≥80 mmHg and, SBP<140 mmHg and DBP<90 mmHg, and no treatment with antihypertensive medication.
Hypertension based on traditional criteria was defined as SBP≥140 mmHg, DBP≥90 mm Hg, and/or current use of an antihypertensive medication.
In this group, 39% were classified as hypertensive based on SBP only, 43% based on DBP only, and 18% based on SBP and DBP.
In this group, 13% were classified as hypertensive based on SBP only, 2% on DBP only, 4% based on SBP and DBP, and 80% based on use of antihypertensive medications.