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. 2018 Aug 23;7(11):e1500107. doi: 10.1080/2162402X.2018.1500107

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© 2018 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 2. — 3’ UTR-mediated control of PD-L1 expression during adipogenesis. (a) Diagram of the pGL3-Cd274/Pd-l1 promoter reporter construct. (b) IFNγ stimulation of Cd274 promoter-driven luciferase in B16 and 3T3-L1 cells. (c) Cd274 promoter-driven luciferase reporter activity before and after adipogenesis. (d) Diagram of the pmirGLO-CD274 3’UTR reporter construct. (e) Cd274 3’UTR luciferase reporter activity before and after adipogenesis.