Skip to main content
Nucleic Acids Research logoLink to Nucleic Acids Research
. 2018 Sep 7;46(19):10533. doi: 10.1093/nar/gky819

Systematic editing of synthetic RIG-I ligands to produce effective antiviral and anti-tumor RNA immunotherapies

Janghyun Lee 1,#, Eun-Byeol Park 2,#, Jiyoun Min 2,#,3, Si-Eun Sung 1,#, Yejin Jang 3, Jin Soo Shin 3, Dongmin Chun 2, Ki-Hun Kim 1, Jihyun Hwang 1, Mi-Kyung Lee 1,3, Yun Young Go 3, Dohyeong Kwon 2, Meehyein Kim 3,, Suk-Jo Kang 2,, Byong-Seok Choi 1,
PMCID: PMC6212841  PMID: 30202915

Nucleic Acids Res 2018; 46 (4): 1635-1647. doi: 10.1093/nar/gky039

The authors of the above-cited article request its retraction. The authors have reported that some of the findings and conclusions of the article cannot be relied upon. Specifically, the original data behind Figures 1, 2, 3, 6B, and 6C could not be located and the results could not be replicated. However, the other findings regarding the antiviral and anti-tumoral effect of the synthetic RIG-I ligands still hold true.

The corresponding authors take full responsibility for a failure to follow proper quality control over the production, validation and dissemination of that data. All authors agree with this request and the information provided in this notice.

The Editors commend the authors for being forthcoming and disclosing this issue.

Authors Contributions: BC, SK, MK, JL conceived and designed the study, wrote and revised the paper. JL, EP, JM, SS, YJ, JS, DC, KK, JH, ML, YG, DK and MK performed the experiments and/or acquired the data. All authors analyzed the data and approved the manuscript.


Articles from Nucleic Acids Research are provided here courtesy of Oxford University Press

RESOURCES