Figure 1.

IOP is not affected by microfibril deficiency. Fbn1^{Tsk /+} (red symbols) and wt mice (blue symbols) had similar IOPs at three, six, nine, and 12 months of age (A). Central cornea thickness measured by SD-OCT imaging (B, red lines) was significantly thinner in Fbn1^{Tsk /+} mice at three, six, and nine months (C). Tonometer calibration was not affected by difference in corneal thickness (D, black lines: linear best fits, 10 wt and six Fbn1^{Tsk /+} mice). Open symbols: individual mice, closed symbols: mean ± SD. Numbers of mice indicated in italics below each group (A, C). Representative SD-OCT images are from three-month-old mice (B).