Figure 1.
Effect of DR2B and DR2C extracts (100–500 µg/mL) on the oxidative damage induced by tert-butyl hydroperoxide (tBOOH; 5 μM) in Caco2 cells under normoxia and CoCl2-induced hypoxia. The pro-oxidant agent tBOOH was added to cells after a 24 h pre-treatment with the extracts. (A,C) Cell viability expressed as % of control. (B,D) Lactate levels normalized to the number of viable cells. Data are mean ± SE from two independent biological replicates, each one performed in two technical replicates (n = 2). * p < 0.05 and ** p < 0.01 vs. tBOOH by ANOVA followed by Dunnett’s multiple comparison post-test.