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. 2018 Oct 9;23(10):2572. doi: 10.3390/molecules23102572

Figure 2.

Figure 2

(a) CD melting curves for native RNA r(CGCGCG)2 (back line), r(CGC[m8Gm]CG)2 containing one m8Gm (blue line), and r(C[m8Gm]C[m8Gm]CG)2 containing two m8Gms (red line). (b) CD melting curves for RNA sequences containing an AU base pair, native RNA r(CGCGUGCG)/r(CGCACGCG) (back line), r(CGCGUGCG)/r(C[m8Gm]CAC[m8Gm]CG) having two m8Gms in one strand (blue line), r(C[m8Gm]CGU[m8Gm]CG)r(C[m8Gm]CAC[m8Gm]CG) having four m8Gms in two strands (red line). In 5 mM sodium phosphate buffer (pH 7.0), 7 M NaClO4 concentrations (0.15 mM base concentration).