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. 2018 Aug 25;13(7):751–768. doi: 10.1080/15592294.2018.1504592

Table 2.

Proteins up-regulated by KLF4-mCpG binding at the enhancer regions of the gene in human glioblastoma cells.

Symbol Full name Functions
ABLIM1 Actin Binding LIM Protein 1 Actin binding
CNIH4 Cornichon Family AMPA Receptor Auxiliary Protein 4 G protein-coupled receptors (GPCRs) trafficking
DLGAP4 SAP90/PSD-95-Associated Protein 4 Molecular organization of synapses and neuronal cell signaling
EFR3B EFR3 Homolog B Involved in localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane
FHOD3 Formin Homology 2 Domain Containing 3 Actin filament polymerization in cardiomyocytes
LMNA Lamin A/C Involved in nuclear stability, chromatin structure and gene expression
LMO7 LIM Domain 7 Involved in protein-protein interactions.
MAPKAPK3 Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 Signaling in both mitogen and stress responses.
NGEF Neuronal Guanine Nucleotide Exchange Factor Activates the GTPases RHOA, RAC1 and CDC42
PHLDB2 Pleckstrin Homology Like Domain Family B Member 2 Involved in the assembly of the postsynaptic apparatus
RHOC Ras Homolog Family Member C Promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility
SAMD9 Sterile Alpha Motif Domain Containing 9 Regulate cell proliferation and apoptosis
TMCO3 Transmembrane And Coiled-Coil Domains 3 Coupled with the export of monovalent cations
UGDH UDP-Glucose 6-Dehydrogenase Synthesize extracellular matrix component glycosaminoglycans
BLK B Lymphocyte Kinase Cell development, differentiation and signaling
VASP Vasodilator Stimulated Phosphoprotein Involved in a range of processes dependent on cytoskeleton remodeling and cell polarity