Figure 4.

Analytes significantly associated with changes in % FEV₁ over entire study. Estimated increase in % FEV₁ given a 1-log unit change in the analyte when comparing two individuals with the same baseline FEV₁ in a given week (mean ± standard error). Analytes are ordered from left to right on the basis of decreasing association significance. Analytes that increased during the study (red) and decreased during the study (blue) are included. MMP = matrix metalloproteinase 9; NGAL = neutrophil gelatinase-associated lipocalin; PARK = pulmonary and activation regulated chemokine; SHBG = sex hormone–binding globulin; SPD = pulmonary surfactant–associated protein D; VEGF-D = vascular endothelial growth factor-D.