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. 2018 Sep 13;23(9):2341. doi: 10.3390/molecules23092341

Figure 3.

Figure 3

Cluster dendrogram of 77 quadruplex binding proteins based on their amino acid compositions constructed using R package pvclust and bootstrap resampling (n = 10,000) with average cluster method. For precise cluster determination, AU values equal to or greater than 95 were chosen as cut-off criterion; the three resulting main clusters (A,B,C) are marked. Protein symbols are highlighted either in red (only RNA quadruplex binding), in blue (only DNA quadruplex binding), or in green (both RNA and DNA quadruplex binding).