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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Neuroimage. 2018 Sep 30;184:964–980. doi: 10.1016/j.neuroimage.2018.09.076

Figure 4: Monte Carlo dictionary approach yields physically-interpretable parameters consistent with histology.

Figure 4:

(a) Histology of a slice in the spinal cord of a rat which underwent surgery, stained with SMI312 immunohistochemistry. Darker colors indicate more neurofilaments present inside axons. (b) Representative map of axonal density index f obtained with our Monte Carlo dictionary approach, laid atop a fractional anisotropy (FA) map. (c) Effect of Wallerian degeneration (WD) on selected parameters from our approach and from popular closed-form models of the microstructure. Vertical bars indicate the 95% confidence interval on βWD. Non-significant (ns) corresponds to p > 0.05; * to p ≤ 0.05; ** to p ≤ 0.01; *** to p ≤ 0.001; **** to p ≤ 0.0001.