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Journal of Thoracic Disease logoLink to Journal of Thoracic Disease
. 2018 Oct;10(Suppl 29):S3500–S3506. doi: 10.21037/jtd.2018.05.115

Focus on specific disease-part 2: the European Society of Thoracic Surgery chest wall database

Benedetta Bedetti 1,, Davide Patrini 2, Luca Bertolaccini 3, Roberto Crisci 4, Piergiorgio Solli 3, Joachim Schmidt 1, Marco Scarci 2
PMCID: PMC6230824  PMID: 30510785

Abstract

Background

Data collection has gained a great importance in numerous areas in the last years and also in the medical field. Collecting data is the key to knowledge and consequently improving data quality is fundamental, as the results of the data analysis can have a large impact on the clinical practice.

Methods

Collected data can be employed to assess the performance of surgeons or institutions and to implement hospital´s performance and productivity. The chest wall database is one of the satellites composing the European Society of Thoracic Surgery (ESTS) database and includes data on risk factors, surgical techniques, processes of care and outcomes related to chest wall pathologies. The participation to the registry is free and voluntary for the ESTS members. The ESTS chest wall database includes data on risk factors, surgical techniques, processes of care and outcomes related to chest wall pathologies. The collected data are designed for quality control and performance audit. Acquired data are anonymous, independently accessed and encrypted on a Dendrite platform, which provides data security and regular backups. The registry is managed by an external company (KData Clinicak Srl), which works together with the database committee in revising and updating periodically the database.

Results

The ESTS chest wall database is structured in four main sections: preoperative, intraoperative, postoperative and follow up. For each procedure registered in the database are collected a number of different variables regarding the patients’ characteristics, the surgical technique, the postoperative course until the discharge and also follow up data. Correction of pectus excavatum is the most common procedures registered in 2017 (392 patients, 67% of all data), followed by pectus bar removal (159 patients, 27% of all procedures).

Conclusions

The ESTS chest wall database is an ambitious European project, which aims to standardize all chest wall procedures in all their aspects.

Keywords: European Society of Thoracic Surgery database (ESTS database), ESTS chest wall, big data

Introduction

Data collection has gained a great importance in numerous areas in the last years and also in the medical field. Collecting data is the key to knowledge and consequently improving data quality is fundamental, as the results of the data analysis can have a large impact on the clinical practice (1,2). Collected data can be employed to assess the performance of surgeons or institutions and to implement hospital’s performance and productivity.

The European Society of Thoracic Surgery (ESTS) database is a multi-institutional and international registry, where the data are collected using a protected online platform (https://ests.kdataclinical.it) (3). To date, up to 15,000 new cases are registered in the database annually from 24 different countries, in details from 170 European and 15 non-European thoracic surgery units (4).

The chest wall database is one of the satellites composing the ESTS database and it collects data about the whole spectrum of chest wall diseases, like tumors, traumas or malformations (Table 1).

Table 1. Spectrum of diseases managed in the ESTS chest wall database.

Congenital chest wall defects
   Pectus excavatum (Nuss and Ravitch procedure)
   Pectus carinatum (Abramson and modified Ravitch procedure)
   Pectus arcuatum
   Mixed defects
Chest wall tumors
   Primary tumors of ribs/sternum
   Metastatic disease
Traumas
   Rib/Sternal resection and reconstructions

ESTS, European Society of Thoracic Surgery.

Methods

Aim and characteristics of the chest wall database

The ESTS chest wall database includes data on risk factors, surgical techniques, processes of care and outcomes related to chest wall pathologies. These data are designed for quality control and performance audit. The registry comprehends the whole spectrum of the chest wall diseases in the form of a detailed database with the aim to find out the best practice at European (and non-European) level in order to develop guidelines and establish a standard to improve the outcome. A composite performance score (CPS) was created to assess the outcomes in different aspects of surgical practice of the participating thoracic surgery units (5,6). Monitoring of implants durability, possible complications and bad reactions in patients undergoing correction of chest wall deformities are highlights for the data collection and open some research possibilities. Data on patients’ surveillance after a chest wall procedure are also collected in the registry.

In the last 20 years, chest wall surgery has undergone a considerable growth in technique and material used for reconstruction (7). In fact, many techniques and materials are currently used from different thoracic surgeons in different areas, as so far there are no guidelines for the management of this kind of diseases. The chest wall database is determined to fulfill this purpose.

Another main objective of the database is to endorse the cooperation between international societies. The Society of Thoracic Surgeons General Thoracic Surgery Database (STS GTSD) and the ESTS Registry Task Force already have a cooperation since 2012 (8). The two societies database task forces meet annually to plan future research projects. In the last years were published some studies from the joint cooperation of the two registries (4), after the data harmonization and standardization between the databases.

Participation

The participation to the registry is free and voluntary for the ESTS members. At least one staff member should retain an ESTS membership and the participants have to request and obtain a personal login account completing the specific application form, which can be downloaded from the ESTS homepage (http://www.ests.org/collaboration/database_registration_form.aspx).

Every single contributor/unit has several benefits besides the obvious advantages for the medical community. In fact, every thoracic surgery unit participating to the database can access its own data collected in a standardized ESTS-endorsed dataset, which can be downloaded and used for internal analysis, statistics or research. Furthermore, the participants will receive a feedback regarding the quality of their data and performance compared to the international benchmarks. Every participating thoracic surgery unit can access the ESTS certification program (http://www.ests.org/collaboration/ests_quality_certification_programme.aspx) and can submit a research project to the ESTS database task force to access data derived from the entire database (http://www.ests.org/collaboration/ests_database_rules_for_publications_and_presentations.aspx).

Data collection

Acquired data are anonymous, independently accessed and encrypted on a Dendrite platform, which provides data security and regular backups. The registry is managed by an external company (KData Clinicak Srl), which works together with the Database Committee in revising and updating periodically the database. Single institutions and national registries can upload data in the database (9,10). Every year the ESTS Registry Annual Report (Silver Book) is published on the ESTS homepage (http://www.ests.org/collaboration/database_reports.aspx) including all data collected during the year (Figure 1).

Figure 1.

Figure 1

Data collected in the chest wall database (source from the Silver Book 2016).

Results

The ESTS chest wall database is structured in four main sections: preoperative, intraoperative, postoperative and follow up. For each procedure registered in the database are collected a number of different variables regarding the patients’ characteristics, the surgical technique, the postoperative course until the discharge and also follow up data (Tables 2,3). Figure 2 shows the number of collected procedures for chest wall deformities until November 2017. In 2016, 2,534 procedures in total were registered in the database according to the silver book and the vast majority of these procedures consisted of surgery for correction of chest wall deformities. Correction of pectus excavatum is the most common procedures registered in 2017 (392 patients, 67% of all data), followed by pectus bar removal (159 patients, 27% of all procedures). Figure 3 shows the correlation between age and gender. Males are generally more affected than females and most patients undergo the procedure in a young age (<40). Figure 4 shows the data regarding the materials used for reconstruction in patients undergoing surgery for pectus excavatum. Figure 5 describes the completeness of the collected data. The data have been collected from 32 hospitals from many European and non-European countries, in particular Brazil. In the supplementary is described in details the core dataset of the chest wall database in all its sections.

Table 2. Structure of the ESTS chest wall database.

Preoperative
   General patients’ characteristics
   Diagnosis
   Neoadjuvant chemo/radiotherapy
   How defect affects patients (for congenital chest wall diseases)
   Lung function and blood gas analysis
   Comorbidities
Intraoperative
   Chest wall subgroup (chest wall, costal cartilage, chest wall incision, reconstruction, rib, thoracoplasty)
   Type of procedure
   Reconstruction (technique and material)
   Margins
   Analgesia (epidural, localanesthetic, pericostal block)
Postoperative
   Complication
   Outcome at discharge, at 30 and 90 days
   Length of hospital stay
   Patients satisfaction at discharge
   Length of epidural analgesia
   Time to return to work
Follow up
   Dead/alive
   For Nuss procedures: (I) bar allergic reaction; (II) bar displacement and degree of displacement
   Required reoperations
   Wound infections
   For rib fixation/chest wall reconstruction: reaction to different materials (allogenic/biologic better than artificial?)
   Chronic pain syndrome
   Other long-time complication

ESTS, European Society of Thoracic Surgery.

Table 3. Intraoperative characteristics in details.

Congenital defects
   Correction of pectus carinatum (open/minimally invasive)
   Correction of pectus excavatum (open/Nuss)
   Pectus silicon implant
   Correction of pectus arcuatum
   Mixed deformity
   Pectus bar removal
   Technique & materials
      With/without sternal fixation
      Number and type of bars/stabilizators (in case of removal: end of planned treatment, allergy to metal, repeated dislodgement, chronic pain)
      Type of silicone implants
Rib and sternal procedures (traumas)
   Resection
   Fixation (flail chest)
   Details
      Indications (acute trauma, malunion, post surgical fixation, chronic pain, inability to wean from ventilator)
      System used (abiomet, synthes, stratos/stracos, acute innovation rib lock, gunze absorbable pins, orthopedic non-thoracic specific devices)
Chest wall tumors (primary malignant/metastatic)
   Resection with reconstruction
   Resection without reconstruction (no needed, covered by scapula)
   Details
      Size and position of resection
      Number and site of resected ribs
      Technique/material of reconstruction (prostesis, muscle flap, myocutaneus flap, omentum)

Figure 2.

Figure 2

Total number of chest wall procedures registered in 2017 (updated until 11/2017).

Figure 3.

Figure 3

Chest wall procedures related to gender and age (updated until 11/2017).

Figure 4.

Figure 4

Data about material used to reconstruction in patients undergoing pectus excavatum.

Figure 5.

Figure 5

Completeness of the collected data.

Conclusions

The ESTS chest wall database is an ambitious European project, which aims to standardize all chest wall procedures in all their aspects, starting from the preoperative preparation, continuing with the surgical technique and helping treating complications. It has the potential to increase the number of collected data within the next years, taking account of the fact that currently only 15% of the European thoracic surgery units are contributing to the registry. Each thoracic surgery department should understand the advantages that imply joining the database, as single unit and as part of the whole group to improve the thoracic surgery practice around Europe.

ESTS preoperative chest wall.

Date of thorsurgprocs
Age at surgery
Height
Weight
BMI
ASA 1: normal healthy individual, 2: mild systemic disease, 3: severe systemic disease not incapacitating, 4: incapacitating systemic disease—constant threat to life, 5: patient moribund—not expected to survive 24 hours
MRC score 0: 1, 1: 2, 2: 3, 3: 4, 4: 5
Cardiac comorbidity 1 0: none, 1: coronary artery disease, 2: any previous cardiac surgery, 3: current treatment for hypertension, 4: current treatment for arrhythmia, 5: current treatment for cardiac failure
Cardiac comorbidity 2 0: none, 1: coronary artery disease, 2: any previous cardiac surgery, 3: current treatment for hypertension, 4: current treatment for arrhythmia, 5: current treatment for cardiac failure
Cardiac comorbidity 3 0: none, 1: coronary artery disease, 2: any previous cardiac surgery, 3: current treatment for hypertension, 4: current treatment for arrhythmia, 5: current treatment for cardiac failure
Other comorbidities 1 0: none, 1: insulin-dependent diabetes, 2: serum creatinine >2 mg/dL, 3: CVA, 4: chronic kidney failure, 5: COPD, 6: gastric ulcer, 7: liver disease, 8: connective tissue disease, 9: myasthenia gravis, 10: previous malignancy, 11: other, 12: gastro-esophageal reflux
Other comorbidities 2 0: none, 1: insulin-dependent diabetes, 2: serum creatinine >2 mg/dL, 3: CVA, 4: chronic kidney failure, 5: COPD, 6: gastric ulcer, 7: liver disease, 8: connective tissue disease, 9: myasthenia gravis, 10: previous malignancy, 11: other, 12: gastro-esophageal reflux
Other comorbidities 3 0: none, 1: insulin-dependent diabetes, 2: serum creatinine >2 mg/dL, 3: CVA, 4: chronic kidney failure, 5: COPD, 6: gastric ulcer, 7: liver disease, 8: connective tissue disease, 9: myasthenia gravis, 10: previous malignancy, 11: other, 12: gastro-esophageal reflux
Urgency 0: elective, 1: urgent, 2: emergency
ECOG 0: fully active, 1: light work only, 2: mobile >50% waking hours, 3: mobile <50% waking hours, 4: immobile & unable to self-care
FEV1, litres
FEV1, percent
FEVC, litres
PpoFEV1, percent
FVC, percent
FEV1, percent
DLCO, percent
PpoDLCO, percent
Other diagnosis
Diagnosis 0: lung cancer (NSCLC), 6: empyema (acute: phase I/II), 1: lung cancer (SCLC), 2: oesophageal cancer, 3: mesothelioma, 4: lymphoma, 5: thymic tumors, 7: empyema (chronic), 8: chronic pleural inflammation, 9: pulmonary TB, 10: COPD, 11: interstitial lung disease, 12: pneumothorax, 13: trauma, 14: achalasia, 15: gastro-oesophageal reflux, 16: paraoesophageal hernia, 17: emphysema, 18: Zenker’s diverticulum, 19: pulmonary metastasis, 20: carcinaoid, 21: other, 22: chest wall condition
Morphology 0: Non-neoplastic, 1: neoplastic benign, 2: neoplastic malignant primary, 3: neoplastic malignant secondary
Smokinghistory 0: never smoked, 1: past smoker (stopped >1 month prior to surgery), 2: current smoker, 3: unknown
Haller index value
CT scan 0: no, 1: yes
Shortness of breath 0: no, 1: yes
Chest pain 0: no, 1: yes
Arrhythmias 0: no, 1: yes
Palpitations 0: no, 1: yes
Low selfesteem 0: no, 1: yes
Psychological 0: no, 1: yes
Other symptom
Scoliosis 0: no, 1: yes
Marfan 0: no, 1: yes
Ehlers danlos 0: no, 1: yes
Cardiac disease 0: no, 1: yes
Previous cardiac surg 0: no, 1: yes
Previous chest surg 0: no, 1: yes

ESTS operative chest wall.

Group definition 0: lung, 1: pleura, 2: chest wall, 3: trachea: bronchus, 4: mediastinum, 5: upper GI, 6: diaphragm
Group other procedure
VATS 0: no, 1: yes
Chest wall subgroup 0: chest wall, 1: costal cartilage, 2: chest wall incision, 3: reconstruction, 4: rib, 5: thoracoplasty
Chest wall procedures 0: biopsy of chest wall lesion, 1: creation of thoracic stoma, 2: excision of chest wall lesion, 3: repair of chest wall, 4: excision/repair of chest wall, 5: correction of chest wall defects
Qualifier excision of chest wall lesion 0: distant flap, 1: local flap, 2: microvascular transferred flap
Qualifier for repair of chest wall 0: plugging flail chest, 1: suture, 2: osteosynthesis
Excision repair qualifier 0: prosthesis, 1: muscle flap, 2: myocutaneous flap, 3: omentum
Costal cartilage procedure 1: excision of costal cartilage, 2: excision of xifisternum, 3: fixation of costal cartilage
Chest wall incision procedures 0: exploratory median sternotomy, 1: exploratory thoracotomy, 2: mini thoracotomy, 3: previous chest wall incision
Correction of chest wall defects qualifier 0: pectus bar removal, 1: pectus carinatum correction, 2: pectus excavatum correction, 3: pectus silicon implant, 4: pectus arcuatum, 5: mixed deformity, 6: pectus repair
Rib procedures 0: rib resection, 1: rib resection for drainage, 2: rib fixation
Qualifier for rib resection 0: biopsy, 1: for pain, 2: fracture
Thoracoplasty procedures 0: plombage procedure, 1: thoracoplasty procedure
Qualifier for plombage 0: insertion of plomb, 1: removal of plomb
Qualifier for thoracoplasty 0: limited thoracoplasty, 1: schede thoracoplasty, 2: total thoracoplasty
Costal cartilage procedures 1: excision of costal cartilage, 2: excision of xifisternum, 3: fixation of costal cartilage
Qualifier pectus carenatum 0: with internal fixation, 1: without internal fixation
Rib sternal fixation 1: referral for surgery, 2: acute trauma, 3: malunion, 4: post-surgical fixation, 5: chronic pain, 6: inability to wean from ventilator
Flail chest 0: no, 1: yes
Surgery 0: no, 1: yes
System used 1: abiomet, 2: synthes, 3: stratos/stracos, 4: acute innovation rib lock, 5: gunze absorbable pins, 6: orthopedic non-thoracic specific devices
Number of plates used
Number of screws used
Acute trauma and fixation within 48 h 0: no, 1: yes
Type of surgery 1: talc pleurodesis, 2: local resection, 3: other
Reoperation 0: no, 1: yes
Metallic implants 0: no, 1: yes
System adopted correction chest wall defects 1: abiomet, 2: synthes, 3: 3D medical, 4: other proprietary, country specific device
Number of bars 1: 1, 2: 2, 3: 3
Number of stabilizers 1: 1 per bar, 2: 2 per bar, 3: no stabilizers, 4: additional sutures
Titanium bars 0: no, 1: yes
Lactosorb 0: no, 1: yes
Carinatum stabilization 0: no, 1: yes
Time from first operation
Cause for removal 1: end of planned treatment, 2: allergy to metal, 3: repeated dislodgement, 4: chronic pain
Chest wall resection with or without repair 1: primary chest wall tumour, 2: secondary malignancy invading the chest wall
Site of resection/chest wall resection repair 1: 1st to 3rd rib, 2: 4th to 9th rib
Location resection 1: anterior location, 2: posterior location
Covered by scapula 0: no, 1: yes
Extended resection 0: no, 1: yes
Reconstruction performed 0: no, 1: yes
Device bars 1: stratos, 2: synthes, 3: other
Margins 1: positive margins, 2: less than 1 cm, 3: 1 to 3 cm, 4: >4 cm
Operative technique nuss 0: no, 1: yes
Operative technique park 0: no, 1: yes
Operative technique pillegard 0: no, 1: yes
Operative technique other 0: no, 1: yes
Comments operative technique
Stabilizer used
Comments stabilizer
Crane technique 0: no, 1: yes
Vacuum bell 0: no, 1: yes
Other sternal elevation 0: no, 1: yes
Comments sternal elevation
Epidural 0: no, 1: yes
Local anesthetic 0: no, 1: yes
Pericostal block 0: no, 1: yes
Comments adjuvant to anesthesia
Correction method
Type surgery carinatum
Pectus brace
Associate physio therapy manoeuvres 0: no, 1: yes
Reabsorbable pericardium 0: no, 1: yes
Patch 0: no, 1: yes
Titanium bars excision repair chest wall 0: no, 1: yes
Number of ribs resected
Pleurectomy pleurodesis* 0: pleurectomy, 1: chemical pleurodesis, 2: mechanical pleurodesis
Prev chest wall incqualifier* 0: debridement, 1: procedure for sinus, 2: removal of wires, 3: reopening, 4: repair with flap, 5: resuture
Reason no surgery*
Type of reconstruction* 1: mesh, 2: pericardial patch, 3: absorbable pericardial patch, 4: metylmethacrylate sandwich, 5: titanium bars, 6: titanium plus pericardium, 7: custom made patient-matched titanium implants

*, denotes fields multichoice.

ESTS postoperative chest wall.

Date of discharge
Complication 1 0: none, 1: air leak >5 days, 2: anastomotic leak (conservative), 3: anastomotic leak (requiring surgery), 4: ARDS, 5: atrial arrhythmia RX postop, 6: bronchopleural fistula, 8: atelectasis, 9: cardiac failure, 10: cerebro-vascular complications, 11: chylothorax, 12: conduit ischaemia, 13: delirium, 14: DVT, 15: empyema, 16: initial ventilation >48 hours, 17: multisystem failure, 18: myocardial infarct, 19: phrenic nerve injury, 20: pneumonia, 21: pulmonary embolism, 22: pulmonary oedema, 23: recurrent nerve palsy, 25: renal failure, 24: reintubate, 28: unexpected admission to ICU, 26: reoperation for bleeding, 27: tracheostomy, 29: ventricular arrhythmia RX postop, 30: wound infection, 31: other
Complication 2 0: none, 1: air leak >5 days, 2: anastomotic leak (conservative), 3: anastomotic leak (requiring surgery), 4: ARDS, 5: atrial arrhythmia RX postop, 6: bronchopleural fistula, 8: atelectasis, 9: cardiac failure, 10: cerebro-vascular complications, 11: chylothorax, 12: conduit ischaemia, 13: delirium, 14: DVT, 15: empyema, 16: initial ventilation >48 hours, 17: multisystem failure, 18: myocardial infarct, 19: phrenic nerve injury, 20: pneumonia, 21: pulmonary embolism, 22: pulmonary oedema, 23: recurrent nerve palsy, 25: renal failure, 24: reintubate, 28: unexpected admission to ICU, 26: reoperation for bleeding, 27: tracheostomy, 29: ventricular arrhythmia RX postop, 30: wound infection, 31: other
Complication3 0: none, 1: air leak >5 days, 2: anastomotic leak (conservative), 3: anastomotic leak (requiring surgery), 4: ARDS, 5: atrial arrhythmia RX postop, 6: bronchopleural fistula, 8: atelectasis, 9: cardiac failure, 10: cerebro-vascular complications, 11: chylothorax, 12: conduit ischaemia, 13: delirium, 14: DVT, 15: empyema, 16: initial ventilation >48 hours, 17: multisystem failure, 18: myocardial infarct, 19: phrenic nerve injury, 20: pneumonia, 21: pulmonary embolism, 22: pulmonary oedema, 23: recurrent nerve palsy, 25: renal failure, 24: reintubate, 28: unexpected admission to ICU, 26: reoperation for bleeding, 27: tracheostomy, 29: ventricular arrhythmia RX postop, 30: wound infection, 31: other
Major cardiopulmonary complications 0: no, 1: yes
Date of death
Cause of death 0: death related to this operation, 1: death related to another operation, 3: death after discharge clearly unrelated to this operation
Outcome at discharge 0: alive at discharge, 1: died in hospital
Outcome at 30 days 0: alive at 30 days, 1: dead at 30 days
Notes
unexpected return 0: no, 1: yes
Re-admission to any hospital within 30 days discharge 0: no, 1: yes, 2: unknown
Outcome at 90 days 0: death, 1: alive, 3: unknown
Length of hospital stay
Length of surgery min
VAS score 1: 1, 2: 2, 3: 3, 4: 4, 5: 5, 6: 6, 7: 7, 8: 8, 9: 9, 10: 10
Patients satisfaction at discharge 1: 1, 2: 2, 3: 3, 4: 4, 5: 5, 6: 6, 7: 7, 8: 8, 9: 9, 10: 10
Length of epidural analgesia
Time to return to work
Entryid
Any pectus recurrence with bar removal 0: no, 1: yes
Mortality with bar removal surgery 0: no, 1: yes
Bar allergic reaction 0: no, 1: yes
Bar displacement 0: no, 1: yes
Degree displacement
Required reoperation 0: no, 1: yes
Comments bar displacement
Pneumothorax requiring chest tube 0: no, 1: yes
Pleural effusion 0: no, 1: yes
Cardiac injury 0: no, 1: yes
Pericardial injury 0: no, 1: yes
Major vascular injury 0: no, 1: yes
Lung injury 0: no, 1: yes
Trocar related injury 0: no, 1: yes
Describe anest related injury
Other complication 0: no, 1: yes
Comments complications
Anesthesia related injury 0: no, 1: yes
Thoracic outlet syndrome 0: no, 1: yes
Pericarditis 0: no, 1: yes
Specify complication

ESTS follow up chest wall.

Date last followup
Date of death
Alive 0: no, 1: yes
Cause of death 0: cardiac, 1: neurological, 2: renal, 3: respiratory, 4: pulmonary embolism, 5: GI, 6: infection, 7: cancer recurrence, 8: other cancer, 9: others, 10: not known
Entryid
Bar allergic reaction flow 0: no, 1: yes
Bar displacement flow 0: no, 1: yes
Degree displacement
Required reoperation 0: no, 1: yes
Comments bar displacement
Developed pectus carinatum flow 0: no, 1: yes
Recurrent pectus excavatum flow 0: no, 1: yes
Cardiac injury flow 0: no, 1: yes
Aortic or vascular injury flow 0: no, 1: yes
Thoracic outlet syndrome flow 0: no, 1: yes
Worsening scoliosis flow 0: no, 1: yes
Chronic pain syndrome flow 0: no, 1: yes
Other complication flow 0: no, 1: yes
Wound infection flow 0: no, 1: yes

Acknowledgements

None.

Footnotes

Conflicts of Interest: The authors have no conflicts of interest to declare.

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