(A–D) One-month ICD fed group: (A) serum appearance, (B) total bilirubin, (C) ALT, and (D) gross liver.
(E–G) TUNEL-stained liver sections: (E) WT, (F) T5KO-NB, and (G) T5KO-HB. Positive cells in green, DAPI in blue. Scale bars, 50 μm (E and F); 100 μm (G).
(H) Liver KC.
(I) Serum sICAM-1.
(J-O) Hepatic (J) neutrophils (K) MPO (L) NE (M) ROS (N) MDA (O) 8-hydroxy-2’-guanosine (8-OH-dG) in serum and urine.
See also Figures S5 and S7