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. 2018 Nov 2;9(86):35687–35704. doi: 10.18632/oncotarget.26286

Figure 2. METTEN study design.

Figure 2

Stratification factors: age, extent of disease (cT2 cN0-1 vs ≥ cT3 or ≥ cN2), and hormone receptor (HR) status. Primary endpoint: pCR in breast and axilla. (HER2, human epidermal growth factor receptor; LVEF, left ventricular ejection fraction; pCR, pathological complete response).