Table 5. Left ventricular ejection fraction (LVEF) in the mITT population.

	Arm A	Arm B
At baseline	N = 38	N = 41
Median (IQR)	65.0% (58.0 to 69.3)	64.0% (61.0 to 68.5)
Week 12	N = 34	N = 40
Median change from baseline (IQR)	–1.5% (–6.6 to 1.2)	–1.0% (–6.8 to 4.0)
LVEF measurement (N, %)			P = 0.032
No decrease or decrease <10%, still above LLN	32 (94.1%)	33 (82.5%)
Decrease <10%, below LLN	1 (2.9%)	1 (2.5%)
Decrease 10–15%, still above LLN	0 (0.0%)	6 (15.0%)
Decrease 10–15%, below LLN	0 (0.0%)	0 (0.0%)
Decrease >15%, still above LLN	1 (2.9%)	0 (0.0%)
Decrease >15%, below LLN	0 (0.0%)	0 (0.0%)
End of treatment	N = 32	N = 37
Median change from baseline (IQR)	–4.0% (–6.0 to –1.8)	–5.0% (–7.5 to –1.0)
LVEF measurement (N, %)
No decrease or decrease <10%, still above LLN	27 (84.4%)	30 (81.1%)	P = 0.409
Decrease <10%, below LLN	1 (3.1%)	0 (0.0%)
Decrease 10–15%, still above LLN	2 (6.3%)	3 (8.1%)
Decrease 10–15%, below LLN	0 (0.0%)	3 (8.1%)
Decrease >15%, still above LLN	2 (6.3%)	1 (2.7%)
Decrease >15%, below LLN	0 (0.0%)	0 (0.0%)

Data are median (IQR) or N (%) unless stated otherwise.

LLN, lower limit of institutional normal; LVEF, left ventricular ejection fraction.