Corrigendum to “Convergence of hepcidin deficiency, systemic iron overloading, heme accumulation, and REV-ERBα/β activation in aryl hydrocarbon receptor-elicited hepatotoxicity” [Toxicol. Appl. Pharmacol. 321 (2017) 1–17]

After publication of this manuscript, the authors were notified by Abcam that the antibody used to quantify hepatic protein levels of iron responsive element (IRE)-binding protein 2 (IREB2; ab181153) was determined to detect not only IREB2 as marketed, but also aconitase 1 (ACO1; aka IREB1). As a result, Fig. 4B depicts total hepatic levels of both IRE-binding proteins (ACO1 and IREB2) rather than IREB2 specifically. However, both ACO1 and IREB2 regulate transcription/translation of IRE-containing genes through the same mechanism. Therefore, this does not significantly impact our conclusions regarding the effect of TCDD on IRE-binding proteins or overall dysregulation of intracellular iron homeostasis.

The authors would like to apologise for any inconvenience caused.