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. 2018 Nov 20;5(6):ENEURO.0219-18.2018. doi: 10.1523/ENEURO.0219-18.2018

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Copyright © 2018 Daviaud et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 4. — Host immune response following NPC and organoid transplants. A, Representative immunofluorescence images of Iba1 in hMito-labeled grafts, at two and four weeks after transplantation. Note the hypertrophied Iba1+ microglia inside the NPC graft, as well as in host brain tissue adjacent to the NPC graft (white arrowhead). B, Representative immunofluorescence images of CD45 in GFP-labeled grafts at indicated time points. Dashed white lines delineate the graft areas. Enlarged images of the boxed area are shown on the right. D: dorsal, V: ventral, M: medial, L: lateral.