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. 2008 Dec 9;13(12):3069–3076. doi: 10.3390/molecules13123069

Table 1.

Effect of geraniol and geranylgeraniol on the growth inhibitory and the membrane damaging activity of farnesol against S. aureus FDA209P.

Terpene Ratioa DPb (h) Leakage of K+ ionsc)(x 10-9 mol μg-1) Initial rate alcohol of leakagec) (x 10-10 mol μg-1 sec-1)
Farnesol + geraniol 1 : 0 13.8 267 8.8
1 : 1 13.5 271 11.1
1 : 2 14.5 395 13.2
1 : 4 16.3 186 3.1
1 : 8 29.0 173 2.4
1 :16 43.7 N.T. d N.T. d
Farnesol+geranylgeraniol 1 : 0 13.8 267 8.8
1 : 1 17.2 28 1.1
1 : 2 14.3 27 0.8
1 : 4 11.3 33 0.8
1 : 8 7.7 15 0.3
1 :16 6.3 N.T.d N.T.d

a Concentration of farnesol was set at 5 and 10 μg mL-1 when the growth inhibitory and the leakage of K+ ions in response to mixed terpenes was observed, respectively; b delay in proliferation; c Assays were performed in triplicate. Results are shown as mean values; d not tested.