Table 2.

In vivo antimalarial activity against P. berghei in mice.

Compound	Dose (mg/kg/day)	Percent suppressiona on day 4	Mice alive on day 28
3.4	100	36.22	0/5
	50	Nil	0/5
3.5	100	21.43	0/5
	50	Nil	0/5
4.2	100	24.31	0/5
	50	6.21	0/5
4.3	100	32.65	1/5
	50	12.24	0/5
4.4	100	58.28	2/5
	50	21.22	1/5
4.5	100	85.29	0/5
	50	48.68	2/5
Chloroquine	8	100	5/5

^a Percent suppression [ CC–T)/C] x 100, where C is parasitaemia in the control group and T is parasitaemia in the treated group.