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. 2019 Jan 1;274:404. doi: 10.1016/j.ijcard.2018.10.031

Retraction notice to “Enhanced IL-17 signalling following myocardial ischaemia/reperfusion injury” [Int. J. Cardiol. 163 (2013) 326–334]

Seán P Barry a, Samir Ounzain b, James McCormick b, Tiziano M Scarabelli c, Carol Chen-Scarabelli c, Louis II Saravolatz c, Giuseppe Faggian d, Alessandro Mazzucco d, Hisanori Suzuki e, Christoph Thiemermann f, Richard A Knight b, David S Latchman b, Anastasis Stephanou b,
PMCID: PMC6250908  PMID: 30449337

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal).

University College of London has undertaken an investigation into allegations received that the above publication contained images that had been deliberately manipulated. The precise details of the allegation are as follows:

  • The images in Figure 5B labelled Control, I/R and I/R+IL-17n both used a section of the same image, with additional features (yellow TUNEL labelled nuclei representing dying cells) having been either added or taken away;

  • In addition, the Control panel in Figure 5B appeared to be a horizontal flip and crop of the Control panel in Figure 4A of "Minocycline inhibits caspase activation and reactivation, increases the ratio of XIAP to smac/DIABLO, and reduces the mitochondrial leakage of cytochrome C and smac/DIABLO" Scarabelli etal, Journal of the American College of Cardiology, 43, 865-874 (2004) https://doi.org/10.1016/j.jacc.2003.09.050

The panel conducting the investigation found that it was clear that the images had been intentionally manipulated as alleged, concluding that research misconduct had occurred. Therefore the editor decided to retract this paper.

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