Table 4. Buried Surface Area between αβ-tubulin dimer and TOG domains or DRP.
| Interface | 1:2:2: sk-Alp14-monomer: αβ-Tubulin: DRP(Å2)* |
1:2:2: sk-Alp14-monomer-SL: αβ-Tubulin: DRP (Å2) |
1:2:1: sk-Alp14-monomer: αβ-Tubulin: DRP-ΔN (Å2) |
|---|---|---|---|
| TOG1 and TOG2-interface 2 | 273 ± 35 | 257 ± 42 | - |
| TOG1-TOG2 dimer-interface 1 | 661 ± 27 | 702 ± 18 | - |
| αβ-tubulin and TOG1 | 752 ± 12 | 786 ± 42 | 804 ± 24 |
| αβ-tubulin and TOG2 | 916 ± 23 | 890 ± 22 | 863 ± 12 |
| β-tubulin and DRP or DRP-ΔN | 842 ± 68 | 873 ± 21 | 846 ± 20 |
| α-tubulin and DRP (inter-αβ-tubulin subunit) |
108 ± 47 | 81 ± 31 | - |
*Interface areas were determined by a single buried surface, and averaged among each non-crystallographic unit in the structure.