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. 2009 Dec 1;14(12):4915–4921. doi: 10.3390/molecules14124915

Table 1.

Potency of the tested oximes to reactivate POX- inhibited human erythrocyte AChE and plasma BuChE at concentrations 100 µM and 10 µM. (%, mean value of three independent determinations, time of inhibition by paraoxon 120 min; time of reactivation by AChE reactivators - 10 min; pH 7.4; temperature 25 °C).

Reactivation (%)
AChE BuChE
Concentration 100 µM 10 µM 100 µM 10 µM
Reactivator Mean S.D. Mean S.D. Mean S.D. Mean S.D.
Pralidoxime6 18.0 0.7 1.3 0.7 5.5 0.1 1.0 0.2
Obidoxime6 96.9 0.7 59.4 0.7 9.9 0.3 2.2 0.3
HI-6 6 16.1 0 3.9 0.7 2.3 0.2 0.8 0.4
K053 21.4 1.4 7.3 0.8 10.7 0.6 1.4 0
K054 0 0 0.4 0 0.2 0 0.2 0
K068 5.4 1.0 1.5 0.4 10.4 0 1.7 0
K071 0 0 0 0 0 0 0 0