Abstract
Background
Diabetes mellitus (DM) increases the risk of tuberculosis disease (TB) and is associated with poor TB treatment outcomes in the general population. We examined the relationship between TB and DM in prison inmates in Peru.
Methods
We analyzed data from a cross-sectional, national survey of adult prison inmates in Peru conducted in 2016. The survey collected sociodemographic and medical information via standardized interview. Medical conditions were defined by self-report. We used multivariate logistic models for adjusted analyses of the relationship between TB and DM.
Results
Of 75,971 inmates, 3,104 (4.3%) reported a history of TB diagnosis. Table 1 shows the characteristics of the TB and non-TB groups. The prevalence of DM was higher in the TB group compared with the non-TB group (4.2% vs. 2.4%; P < 0.001). In multivariate analysis, DM was associated with twice the odds of having had a diagnosis of TB (adjusted OR = 2.2; 95% CI: 1.8–2.7). Male sex, Spanish language, no college/university education, reimprisonment, hypertension, and HIV infection were also associated with increased odds of prevalent TB (Figure 1).
Conclusion
There was a high prevalence of TB among prison inmates in Peru. DM was associated with an increased likelihood of prevalent TB. Our results are consistent with findings in noninstitutionalized populations and underscore the need to implement aggressive screening and treatment interventions for both TB and DM in prison settings.
Table 1: Characteristics of TB and Non-TB Groups in Peruvian Prisons
| Variables | TB group N = 3,104 |
Non-TB group N = 72,331 |
P-value |
|---|---|---|---|
| Age in years, mean ± SD | 35.1 ± 10.4 | 36.1 ± 11.5 | <0.001 |
| Male sex, n (%) | 3,053 (98.3) | 68,516 (93.8) | <0.001 |
| College/University education, n (%) | 8,996 (6.6) | 201 (12.7) | <0.001 |
| Spanish language, n (%) | 2,893 (93.2) | 64,295 (88.2) | <0.001 |
| Reimprisonment, n (%) | 723 (27.0) | 9,110 (16.2) | <0.001 |
| Hypertension, n (%) | 175 (4.7) | 3,399 (5.6) | 0.011 |
| Diabetes mellitus, n (%) | 131 (4.2) | 1,766 (2.4) | <0.001 |
| HIV infection, n (%) | 65 (2.1) | 251 (0.3) | <0.001 |
Disclosures
All authors: No reported disclosures.
Session: 70. Tuberculosis and Other Mycobacterial Infections
Thursday, October 4, 2018: 12:30 PM