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Subsequent recurrence and OS after first recurrence. A, Competing risks regression model for recurrence/progression after first recurrence. Death was considered a competing risk. Half the patients were likely to experience a second recurrence within 2 yr of being treated for a first recurrence. B, Kaplan–Meier estimates of OS after first recurrence. OS decreased from 5.2 yr after first recurrence to 3.7 yr after a second recurrence.
