TABLE 5.

Treatment of Successive Recurrences

Recurrence	No. of Pts.	None	Surgerya	Surgery + RTa	RTa	Chemo	Adjuvant Chemo
First	n = 60	1 (2%)	17 (28%)	23 (38%)	17 (28%)	2 (3%)	7 (12%)
Second	n = 43	8 (19%)	11 (26%)	11 (26%)	11 (26%)	2 (5%)	10 (23%)
Third	n = 23	8 (36%)	4 (17%)	1 (5%)	4 (17%)	6 (27%)	9 (39%)
Fourth	n = 7	3 (43%)	1 (14%)	0	2 (29%)	1 (14%)	1 (14%)
Fifth	n = 1	1 (100%)	0	0	0	0	0

RT: radiation therapy.

^aIncludes patients that received chemotherapy in combination.

“Adjuvant Chemo” category denotes patients who had chemotherapy in combination with any other treatment modalities (ie, Surgery, Surgery + RT, or RT)

None: Patients were observed with serial imaging and did not receive any treatment for the recurrence.