Skip to main content
. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Cortex. 2018 Sep 20;109:141–155. doi: 10.1016/j.cortex.2018.09.006

Table 4.

Neural Correlates of Prosocial Behavior During the Helping Task. Smaller gray matter volume was associated with lower empathic concern and consolation but greater disengagement and impatience in bvFTD and healthy controls (controlling for age, sex, diagnosis, and total intracranial volume). Montreal Neurological Institute (MNI) coordinates given for maximum T- score for the cluster (cluster size > 70 mm3, p<.005, uncorrected).

Anatomical region Cluster
volume
(mm3)		 MNI Maximum
T-score
coordinates
x y z
 Empathic Concern
   Left Midcingulate Cortex* 408 0 −5 51 4.48
   Right Midcingulate Cortex †
   Right Thalamus 1215 3 −24 8 3.80
   Right Midcingulate Cortex 128 2 −26 53 3.35
   Right Midcingulate Cortex 95 14 −33 44 3.20
   Left Thalamus 81 −14 −33 2 2.96
 Consolation
   Right Caudate 284 20 −20 20 3.47
   Right Thalamus †
   Left Caudate 78 −20 −20 20 3.39
   Left Thalamus 716 −5 −21 5 3.30
   Left Midcingulate Cortex 192 −6 −45 50 3.20
 Disengagement
   Left Ventral Striatum 807 −20 12 −8 3.41
   Left Frontoinsula 128 −32 17 −8 2.97
 Impatience
   Right Thalamus* 2336 15 −27 3 5.76
   Left Thalamus* 1877 −9 −24 2 4.74
*

denotes clusters in which voxels remain significant at pFWE<.05.

†

signifies these regions were included in th e cluster above.

Color bars indicate the T-scores.